administered immediately after the surgery and three days after. Methods: EVs were purified by ultracentrifugation and characterized in accordance with ISEV-guidelines, by transmission electron microscopy, flow cytometry and Western Blot.īALB-c mice were subjected to 30 minutes IRI and EVs (1x109) were i.v. In this study, we investigated the potential therapeutic effect of extracellular vesicles (EVs) derived from human liver stem cells (HLSCs) in an in vivo model of IRI-AKI, which subsequently develops into CKD Introduction: Renal ischemia reperfusion injury (IRI) is the major cause of acute kidney injury (AKI) which can progress to chronic kidney disease (CKD).

ISEV gratefully acknowledges the support of the 2022 Annual Conference from our sponsors:įA1: Thursday Featured Abstracts Chair: Clotilde Théry – Institut Curie, PSL Research University, INSERM U932 Chair: Uta Erdbrügger – University of Virginia FA1.2 Human liver stem cell-derived extracellular vesicles interfere with the development of chronic kidney disease in an in vivo experimental model of renal ischemia and reperfusion injuryĮlena Ceccotti 1 Stefania Bruno 2 Giulia Chiabotto 2 Massimo Cedrino 3 Chiara Pasquino 4 Cristina Grange 5 Giovanni Camussi 6ġDepartment of medical science, University of Turin, Torino, Italy 2Department of medical science, University of Turin, Turin, Italy 3Unicyte, Torino, Italy 4Molecular Biotechnology Center, Turin, Turin, Italy 5Department of Medical Sciences, University of Turin, Turin, Italy 6Department of Medical Sciences, Torino, Italy Some names of session chairs may be missing or incorrect because of last-minute declines, acceptances, or other changes.

Names and affiliations of authors are as entered by the submitters. Jan Lötvall (Sweden) Note from the International Organizing Committee IOC Members: Yu Fujita (Japan), Bernd Giebel (Germany), David Greening (Australia), Soazig Le Lay (France), Metka Lenassi (Slovenia), and Ken Witwer (USA) Journal of Extracellular Vesicles: Editor in Chief IOC Chairs: Lorraine O'Driscoll (Ireland), Sophie Rome (France) ISEV2022 International Organizing Committee With an anticipated 1,000+ attendees, ISEV2022 will feature presentations from the top researchers in the field, as well as providing opportunities for talks from students and early career researchers. The ISEV annual meeting is the premier international conference of extracellular vesicle research, covering the latest in exosomes, microvesicles and more. Our vision is to be the leading advocate and guide of extracellular vesicle research and to advance the understanding of extracellular vesicle biology. ISEV's mission is advancing extracellular vesicle research globally. The International Society for Extracellular Vesicles is the leading professional society for extracellular vesicle research.

The Breaking Light by Heather Hansen